Andrology - male diseases >>>> Peyronie disease - causes of development and treatment options

Peyronie disease - causes of development and treatment options.

Peyronie disease is a disease that only men are prone to, as it affects the tissue structure of the inner region of the corpus cavernosum. This is collagenosis (a violation of the formation of collagen), which converts normal tissue into connective tissue. First, fibrous plaques form inside the corpus cavernosum, and gradually a significant part of normal tissue is replaced by fibrous. This effect leads to a curvature of the penis towards the connective tissue formations and a violation of tissue stretching, since the connective tissue is not elastic.

Signs of Peyronie disease usually develop slowly, and acute manifestations of the disease are rare.

With a significant replacement of the cavernous bodies with fibrous tissue, men begin to feel discomfort in the penis during sexual relations, erectile function decreases, the curvature of the penis, even insignificant, becomes visible, in the places where fibrous tissue is spread, the penis seems to be pulled over - it looks like an hourglass.

Untimely access to a doctor - andrologist entails the progression of the disease and, as a consequence: impotence, infertility.

The reasons for the development of Peyronie disease lie in chronic trauma to the tissues of the penis (microtrauma and inflammation), vitamin E hypovitaminosis and calcium deficiency, and metabolic disorders in fat cells.

Peyronie disease is treated with conservative and surgical methods. Peyronie conservative treatment is aimed at inhibiting the uncontrolled division of cells - fibroblasts. For this, anti-inflammatory drugs (glucocorticosteroids) and cytostatics are used. Assign injectable collagenase, lidase at the sites of tissue fibrolization. Injections are carried out in courses of up to three months under the supervision of a physician and renewed if further treatment is necessary.

Surgical treatment involves the excision of the connective tissue areas to prevent their further spread.

It is very important to start Peyronie treatment at a time when the process of tissue fibrolization is only gaining momentum and small areas are affected, which can be painlessly removed.