Immunology and Allergology >>>> DTP vaccine (DPT vaccine)
DTP vaccine (DPT vaccine).
The DTP vaccine is designed to prevent the occurrence of whooping cough, diphtheria and tetanus. The DTP vaccine refers to combination vaccines (killed and inactivated vaccines, where the toxins of the causative agents of tetanus and diphtheria are inactivated, and the causative agent of pertussis is killed) and contains whole microbial cells introduced by three or four times vaccination. The introduction of the vaccine is carried out in the presence of antipyretic drugs, and, if necessary, antihistamines in order to avoid the risk of complications in the form of seizures and allergic reactions.
The name of the vaccine is various in different countries, but the essence of its composition remains the same - DPT vaccine In the United States (diphtheria, pertussis and tetanus) and DTP vaccine in France, in Netherlands, in United Kingdom (diphtheria, tetanus, pertussis).
Possible complications in the post-vaccination period:
- Convulsive syndrome is of two types. In the first type, tonic or clonic seizures develop under conditions of increased body temperature in the first two days after vaccination. Lasts from a few seconds to one or two minutes. May be accompanied by loss of consciousness. In the second type, tonic convulsions develop at normal temperature on the fourth - twentieth day.
- Increased intracranial pressure during the first hours after vaccination.
- Allergic complications (anaphylactic shock, Quincke edema, rash, hemorrhages, arthralgia).
Contraindications to DTP vaccination:
- Diseases of the nervous system in the stage of progression,
- History of afebrile seizures (in the form of nods, stopping gaze in front of you, loss of consciousness),
- Any diseases in the acute stage.
- With the potential for complications from the central nervous system, vaccination is possible, which excludes the components of the whooping cough vaccine.
DTP vaccination scheme:
- The first stage of vaccination is the child's age 2-3 months;
- The second and third stages of vaccination (revaccination) - every 1-2 months;
- The fourth stage of vaccination (revaccination) - one year after the last vaccination.
Revaccination against tetanus and diphtheria (without pertussis component) is carried out at seven, fourteen and then periodically after 10 years until the end of life.
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