Dermatology >>>> Increased keratinization of the skin
Increased keratinization of the skin.
Increased keratinization of the skin in some areas, which is most often observed on the soles of the feet and in the area of the palms, is called keratoderma.
Keratoderma (hyperkeratosis), as a rule, is a hereditary disease, inheritance occurs in an autosomal recessive manner. Disease genes code for keratin cells.
Signs of keratoderma:
- excessive peeling of the skin in the area of the palms and soles of the feet,
- coarsening of the skin, thickening of the skin,
- increased sweating of the palms and feet,
- cracking of the skin in places of coarseness.
The disease of keratoderma refers to dermatoses, affects the upper layers of the dermis, which at the initial stages slightly thicken, over time the skin becomes more coarse.
There are several types of keratoderma, which fit into two groups: diffuse and focal. With diffuse keratoderma, not only skin cells can be affected, but also bone tissue, nail plates and hair, which leads to skeletal deformations, thickening of teeth and hair, nails, which change their shape and deform during the thickening process. Diffuse keratoderma can also lead to keratinization of the tissues of the joints of the extremities. In severe cases, with keratoderma, the motor functions of the phalanges of the fingers may be impaired, which entails the selective removal of the fingers. Focal keratoderma have local (limited) areas of the modified dermis.
Keratoderma is a complex disease with a low effect of treatment, but treatment provides an improvement in the general condition in the area of increased keratinization of the skin, makes life easier for the patient. The causes of keratoderma are associated with many, including hereditary factors, but it was noticed that patients have a lack of vitamin A. This involves the addition of vitamin A in high doses and its derivatives, ointments and creams with keratolytic effect to the main drugs for treatment (neotigazone), retinoids and steroids.
Read
Read
