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What does Glycine help with?

A person’s life is full of anxious and stressful situations, which can lead to disturbances in general well-being, a “loose” nervous system, sleep disturbances and unreasonable worries. A properly functioning human body is able to independently cope with stress and anxiety, since in the human body there is a mechanism that, in moments of excessive emotional reactions, inhibits or normalizes the excitation of the nervous system, extinguishes nervous excitement and leads the human nervous system to a state of relaxation and tranquility. This mechanism is ensured by the work of neurotransmitters that act on neurons of the brain and spinal cord and reduce the quantitative release of excitatory amino acids (for example, glutamic acid). One such neurotransmitter is an organic aliphatic amino acid with the pharmaceutical name Glycine.

What does Glycine help with? The problem of Glycine’s participation in the processes of inhibition of excessive excitation of the nervous system is associated with its quantitative limitations in the composition of neurons. This means that the function of the processes of inhibition of nervous excitations in the tissues of the nervous system is not unlimited. Along with this, there is the problem of artificially replenishing the amount of the aliphatic amino acid Glycine in the biochemical composition of neurons, which is associated with the impermeability of the barrier functions of neuronal tissues - the blood-brain barrier, which prevents the penetration from the bloodstream of both the amino acid Glycine itself and the indirect penetration of substances from which the body itself can synthesize glycine.

It is known that to inhibit nerve impulses in neurons, the body uses only that Glycine that it can synthesize independently. But in medicine there have always been areas of research related to the search for ways to deliver Glycine to neurons in order to enhance the effects of inhibition of nervous excitations. Such studies were carried out with the aim of finding solutions for the treatment of a number of diseases based on states of excessive nervous excitation.

The very discovery of synthetic Glycine is directly related to such a food product as gelatin, from which Glycine was first obtained artificially. But it is also known that this substance is found in foods such as animal proteins (meat, fish, dairy products and their derivatives) and plant proteins (nuts, pumpkin seeds, buckwheat and oats, legumes).

Despite the fact that today there is no direct evidence of the entry of Glycine (or the substance for its synthesis) from the bloodstream into neuronal tissue, pharmaceuticals offer many drugs containing the amino acid Glycine as excipients. There are a number of dietary supplements with the code E-640, which means that the product contains the amino acid Glycine. The pharmaceutical industry produces sublingual lozenges called Glycine.

Glycine is usually recommended as a sedative, relaxing and mild stimulating hypnotic for prolonged nervous tension. It is used to prevent the development of over excitation of the central nervous system.